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Istradefylline 40 mg/working day greater peak ranges and AUC of CYP3A4 substrates in scientific trials. This result wasn't noticed with istradefylline twenty mg/working day. Consider dose reduction of delicate CYP3A4 substrates.modafinil will minimize the level or impact of mavacamten by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Cont
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